Identifying the molecular pathways to greater muscle quality in older adults. Opportunity to take part.

We aim to:

1) Establish a single nuclear transcriptomic atlas of sarcopenia from muscle biopsies from distinctly phenotyped individuals.


2) Explore the influence of lifestyle factors on the composition and molecular phenotype of cells within muscle.

You are being invited to take part in a research study that aims to improve our understanding of changes in muscle mass and strength in relation to different lifestyle factors. The results of this study will be used to inform practice and will be published in a scientific journal. You will receive a copy of your own results on completion of the study. Your results will not be individually identifiable in any published report.

You have been invited to participate in this study due to your age, your lifestyle, and your health status. We are looking for healthy participants, aged over 60 years, who are able to walk without the use of a walking aid.

Participation in the study involves one laboratory visit split into three stages: 1) health screening, 2) physical function assessments, and 3) muscle micro-biopsy. We estimate that the entire laboratory visit (all three stages) will last approximately 90 minutes.

If you would like more information and/or would like to participate in this study, please contact Dr Lewis Macgregor ( or Dr Nidia Rodriguez-Sanchez (

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